According to his blog , the greatest entertainer of Indian Cinema Mr. Amitabh Bachchan is suffering from liver cirrhosis. At least 25% of his liver has been destroyed.  For this reason Mr. Big B undergoes routine Check ups and MRIs. Though Mr. Bachchan is not alcoholic the cirrhosis dates back to his injury during the shooting of the film Coolie.  It was caused due infusion of infected blood from among one the 200 volunteers who donated blood to Mr AB. Details can found at Mr. Bachchan’s Blog.